Interesting post about applying typical big company consulting thinking to startups and product companies from [Silicon Valley Product Group blog]http://www.svpg.com/how-to-kill-innovation/)
In the manufacturing world especially, if your company is struggling with quality or cost issues, then Six Sigma can be very appropriate. It is based on a set of quality management techniques and practices that can significantly reduce costs and defect rates.
Unfortunately, many of those that advocate Six Sigma believe that the principles should be applied throughout the organization, for virtually any business process. But what can be good for removing defects in a manufacturing process can completely destroy the product discovery process and software development.
Please know that I am dead serious when I say this: for companies that depend on innovation, these well-intentioned but misguided people can destroy your company.